News

Say Hi to our new customly developed vector plots

From the beinning in 2005, the R2 team had developed R2-specific visualizations that we felt would do justice to the data that we were presenting. This has resulted in some plots that can only be generated by the R2 engine. For many years we have sticked to raster images (png) files, that were later extended with the option to create an SVG vector copy, to use in your publications.
However, the interactive options on these plots were limited. To enable more interactivity, we started to re-develop our plots from scratch using D3, which is a graphing libray with nearly infinite possibilities.

Using the D3 library, we are replacing our graphs with interactive versions, that will keep on becoming more intereactive over the time to come. Currently this already allows you to hilight or mark samples, pan and zoom in the sample maps, or toggle groups when you use the 'color by' option in grouped plots. In addition, using the d3 library, we have been able to add new visualizations, such as violin plots, or the raincloud plots, that allow for an even more immersive insight into your data.

So please give the new plotting options a testdrive, and let us know what you like / dislike about them. We are always eager to learn how we can improve the R2 platform.

The R2 Team
News

iTHER Precision Medicine Data Scope

With the publication of langenberg et al in European Journal of Cancer titled: "Implementation of paediatric precision oncology into clinical practice: The Individualized Therapies for Children with cancer program 'iTHER'", the data presented in this manuscript is also available in R2

Use the 'iTHER (PMC)' datascope to launch the personalized medicine tools implemented in R2 and see how they have been used in tumor board sessions, to identify potentially targetable events from the profiling data generated at the DKFZ in Heidelberg Germany, or using the Genomics core of the Princes Maxima Center in Utrecht, the Netherlands.

All of these developments would heve been impossible without the feedback and suggestions of the ither entity experts and the data delivery teams at DKFZ and the PMC.

Navigate to the data scope for this resource, using the menu item and start to explore the rich data on 230 pediatric cancer cases that were included in the iTHER and iTHER2.0 studies.