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Alternative names:
age: 10
gender: male
location: posterior fossa, left cerebellar hemisphere, extending to brainstem and through foramen magnum
diagnosis: anaplastic ependymoma
pre-treatment: radiation and chemotherapy
source: recurrent, autopsy
stage: m0 at diagnosis, metastatic recurrence
efs_(months): 31.5
os_(months): 85.4
pathology_of_human_tumor: from initial diagnosis: the sections reveal sheets of cells with small round to oval nuclei with finely speckled chromatin and eosinophilic cytoplasm. the nuclei exhibit palisading and frequently are arranged in pseudo-rosettes around thin-walled vessels and occasional true rosettes. no significant pleomorphism or mitotic activity is noted, and no definite necrosis is identified. from autopsy: increased mitotic activity (10 10 high power fields), larger and more hyperchromatic nuclei, and higher cellularity than the prior specimen.
mouse_strain: cell line
site_of_transplantation: -
protocol: olson lab tissue culture protocol
days_to_p0_p1_p2: -
pi: james m. olson
contact: http://www.btrl.org/product/epd-210fhtc/

entity: ependymoma
subgroup: pfa
curated_lesions: 1q gain

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plot: epd-210fhtc_p3
AMC: OncogenomicsGo to: Main | Pediatric PDX (Olson) portalOpen access