location: posterior fossa, left cerebellar hemisphere, extending to brainstem and through foramen magnum
diagnosis: anaplastic ependymoma
pre-treatment: radiation and chemotherapy
source: recurrent, autopsy
stage: m0 at diagnosis, metastatic recurrence
pathology_of_human_tumor: from initial diagnosis: the sections reveal sheets of cells with small round to oval nuclei with finely speckled chromatin and eosinophilic cytoplasm. the nuclei exhibit palisading and frequently are arranged in pseudo-rosettes around thin-walled vessels and occasional true rosettes. no significant pleomorphism or mitotic activity is noted, and no definite necrosis is identified. from autopsy: increased mitotic activity (10 10 high power fields), larger and more hyperchromatic nuclei, and higher cellularity than the prior specimen.